Circulation Research – SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

Spike

Yuyang Lei, Jiao Zhang, Cara R. Schiavon, Ming He, Lili Chen, Hui Shen, Yichi Zhang, Qian Yin, Yoshitake Cho, Leonardo Andrade, Gerald S. Shadel, Mark Hepokoski, Ting Lei, Hongliang Wang, Jin Zhang, Jason X.-J. Yuan, Atul Malhotra, Uri Manor, Shengpeng Wang, Zu-Yi Yuan, John Y-J. Shyy · 2021

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SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection relies on the binding of…

Stem Cell Biology – Evidence that SARS-Cov-2/COVID-19 spike protein damages hematopoietic stem/progenitor cells

Spike

Magdalena Kucia, Janina Ratajczak, Kamila Bujko, Mateusz Adamiak, Andrzej Ciechanowicz, Vira Chumak, Katarzyna Brzezniakiewicz-Janus, Mariusz Z. Ratajczak · 2021

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Damages cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner. Mounting evidence…

CUREUS – A Potential Role of the Spike Protein in Neurodegenerative Diseases: A Narrative Review

Spike

Stephanie Seneff, Anthony M. K yriakopoulos, Greg Nigh, Peter A. McCullough · 2023

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Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of…

Elsevier – S2 Subunit of SARS-nCoV-2 Interacts with Tumor Suppressor Protein p53 and BRCA: an In Silico Study

Spike

Nishant Singh, AnuradhaBharara Singh · 2020

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Novel coronavirus disease 2019 (COVID-19) is the biggest threat tohuman being globally. Thefirst…

Circulation – Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis

Spike

Lael M. Yonker; Zoe Swank; Yannic C. Bartsch; Madeleine D. Burns; Abigail Kane; Brittany P. Boribong; Jameson P. Davis; Maggie Loiselle; Tanya Novak; Yasmeen Senussi; Chi-An Cheng; Eleanor Burgess; Andrea G. Edlow; Janet Chou; Audrey Dionne; Duraisamy Balaguru , MD; Manuella Lahoud-Rahme , MD; Moshe Arditi , MD; Boris Julg, MD, PhD; Adrienne G. Randolph , MD; Galit Alter, PhD; Alessio Fasano , MD† ; David R. Walt · 2023

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Cases of adolescents and young adults developing myocarditis after vaccination with severe acute…

Molecular Medicine – Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis

Spike

Ioannis P. Trougakos, Evangelos Terpos, Harry Alexopoulos, Marianna Politou, Dimitrios Paraskevis, Andreas Scorilas, Efstathios Kastritis, Evangelos Andreakos, Meletios A. Dimopoulos · 2022

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Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19) pandemic,…

PLOS one – Detection of spike protein in term placentas of COVID-19 vaccinated and/or SARS-CoV-2 infected women

Spike

Catharina Bartmann, Vanessa Schmidt, Michael Mörz, Michael Schwab, Monika Rehn, Bettina Blau-Schneider, Achim Wöckel, Ulrike Kämmerer · 2026

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COVID-19 (Corona Virus Induced Disease-19) caused by the SARS-CoV-2 corona-virus can be a…

MDPI – Detection of Vaccine-Derived Spike Protein Associated with Immune Cell Infiltration in the Heart and Liver

Spike

Michael Mörz, Alberto Donzelli, Robert Llewellyn Clancy, Shigetoshi Sano, Masanori Fukushima and Panagis Polykretis · 2025

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A Report of Two Cases The rapid development and deployment of COVID-19 genetic…